O'Meara defeated Campbell in February, but faced him again on Saturday at Watford Colosseum after a late withdrawal by original opponent 'The Isle of Wight Assassin' Jay Morris.
And the 25-year-old former Dale Youth Club light-middleweight looked vastly composed in his 60-54 points success, showing more variety in his boxing and making better use of the ring.
While Campbell produced a one-dimensional performance and mistimed many of his shots over the six rounds, O'Meara came close to stopping his opponent during the first minute of round four as he threw 30 successive punches.
"I boxed much better against Campbell this time round," said O'Meara, who is now unbeaten in eight outings as a professional. "I knew he was a tough customer - he's physically very strong.
"I went out for the stoppage in the fourth round but I got a bit over-excited. Maybe if I'd kept going it would have come, but I used up a lot of energy, especially in the early rounds.
"Overall this was a good experience for me because I was able to change styles and not be just one-dimensional as Campbell was. My boxing showed that I can mix it up and fight different styles.
"I was disappointed when Morris pulled out, but I've got plenty of time. I've been a pro for only a year, so I will get those fights without a doubt."
Meanwhile, Shepherd's Bush fighter John O'Donnell, who was at ringside to watch his former Dale Youth colleague, is expected to defend his Commonwealth welterweight title some time in September.
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